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A Sparreboom Selected Research

laniquidar (R101933)

5/2002Disposition of docetaxel in the presence of P-glycoprotein inhibition by intravenous administration of R101933.
7/2000Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans.
4/2000The orally administered P-glycoprotein inhibitor R101933 does not alter the plasma pharmacokinetics of docetaxel.

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A Sparreboom Research Topics

Disease

34Neoplasms (Cancer)
11/2016 - 01/2000
7Diarrhea
03/2008 - 01/2000
5Neutropenia
11/2016 - 02/2001
4Ovarian Neoplasms (Ovarian Cancer)
11/2013 - 08/2001
4Fatigue
02/2004 - 01/2000
3Fever (Fevers)
01/2005 - 01/2000
3Breast Neoplasms (Breast Cancer)
02/2004 - 12/2001
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2016 - 01/2016
2Sleepiness
01/2005 - 05/2002
2Thrombocytopenia (Thrombopenia)
10/2001 - 02/2001
2Vomiting
10/2001 - 02/2001
1Lung Neoplasms (Lung Cancer)
03/2008
1Exanthema (Rash)
03/2008
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2008
1Neoplasm Metastasis (Metastasis)
07/2007
1Peripheral Nervous System Diseases (PNS Diseases)
09/2001
1Hypersensitivity (Allergy)
09/2001
1Anorexia
02/2001
1Nausea
02/2001
1Necrosis
02/2001
1Renal Cell Carcinoma (Grawitz Tumor)
02/2001
1Asthenia
07/2000
1Pleural Effusion (Pleural Effusions)
04/2000
1Ascites
04/2000
1Mucositis
04/2000

Drug/Important Bio-Agent (IBA)

11Cisplatin (Platino)FDA LinkGeneric
11/2013 - 01/2000
10Paclitaxel (Taxol)FDA LinkGeneric
09/2012 - 06/2000
8Irinotecan (Camptosar)FDA LinkGeneric
09/2012 - 01/2000
7Docetaxel (Taxotere)FDA Link
11/2016 - 04/2000
7Topotecan (Hycamtin)FDA LinkGeneric
09/2012 - 04/2000
5Pharmaceutical PreparationsIBA
01/2016 - 01/2003
3laniquidar (R101933)IBA
05/2002 - 04/2000
2Midazolam (Versed)FDA LinkGeneric
01/2014 - 12/2008
2Proteins (Proteins, Gene)FDA Link
11/2012 - 01/2007
2Doxorubicin (Adriamycin)FDA LinkGeneric
09/2012 - 01/2005
2CreatinineIBA
08/2008 - 02/2001
2PlatinumIBA
03/2008 - 10/2002
2cremophor ELIBA
10/2001 - 06/2000
1Cytarabine (Cytosar-U)FDA LinkGeneric
02/2016
1Sunitinib (Sutent)FDA Link
01/2014
1Messenger RNA (mRNA)IBA
11/2013
1Cimetidine (Biomet)FDA LinkGeneric
11/2013
1Tyrosine (L-Tyrosine)FDA Link
03/2013
1Phosphotransferases (Kinase)IBA
03/2013
1Imatinib Mesylate (Gleevec)FDA Link
06/2011
1Rosuvastatin Calcium (Crestor)FDA Link
06/2011
1Antineoplastic Agents (Antineoplastics)IBA
10/2009
1Cytochrome P-450 CYP3AIBA
12/2008
1Erythromycin (Erycette)FDA LinkGeneric
12/2008
1Erlotinib Hydrochloride (CP 358,774)FDA Link
05/2008
1BAS 100IBA
05/2008
1Gefitinib (Iressa)FDA Link
03/2008
1ErbB Receptors (EGF Receptor)IBA
03/2008
1Tyrosine Kinase InhibitorsIBA
03/2008
1Dexamethasone (Maxidex)FDA LinkGeneric
07/2007
1Glycoproteins (Glycoprotein)IBA
07/2007
1ElacridarIBA
01/2005
1adriamycinolIBA
01/2005
1Liposomes (Liposome)IBA
03/2004
1Hormones (Hormone)IBA
02/2004
1Cytotoxins (Cytolysins)IBA
02/2004
1Cytostatic AgentsIBA
01/2002
1AnthracyclinesIBA
12/2001
1Lipoproteins (Lipoprotein)IBA
09/2001
1Etoposide (VP 16)FDA LinkGeneric
09/2001
1NeomycinFDA LinkGeneric
05/2001
1GlucuronidaseIBA
05/2001
1Ketoconazole (Nizoral)FDA LinkGeneric
04/2001
1TransferasesIBA
02/2001
1lonafarnib (SCH 66336)IBA
02/2001
1Interferon-gamma (Interferon, gamma)IBA
02/2001
1CamptothecinIBA
02/2001
1Interleukin-12 (IL 12)IBA
02/2001
1EnzymesIBA
02/2001
1Capecitabine (Xeloda)FDA Link
07/2000

Therapy/Procedure

5Drug Therapy (Chemotherapy)
04/2014 - 10/2001
3Therapeutics
04/2014 - 09/2008
2Intravenous Infusions
10/2001 - 01/2000
1Combination Drug Therapy (Combination Chemotherapy)
09/2001
1Drug Tapering
02/2001
1Subcutaneous Injections
02/2001